Rapid Hybridization

Mana cost: {U}
Type: Instant
Set: Bloomburrow Commander #111 (uncommon)
Price: $1.58 USD

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Rapid Hybridization has 13 printings, first in Gatecrash (2013). EDHREC ranks it #209 among Commander cards. It appears most in Hakbal of the Surging Soul decks (17,057 on EDHREC). 7 public decks on TCG run it. It has 2 official rulings.

Legality

commander: legal
legacy: legal
vintage: legal
pauper: not legal
modern: legal
pioneer: legal
standard: not legal
brawl: legal

Public decks that run Rapid Hybridization

Explorers of the Deep - The Lost Caverns of Ixalan Commander, led by Hakbal of the Surging Soul
Family Matters - Bloomburrow Commander, led by Zinnia, Valley's Voice
Odds and Ends - Secret Lair Commander, led by Yennett, Cryptic Sovereign
Quandrix Unlimited - Secrets of Strixhaven, led by Zimone, Infinite Analyst
Quantum Quandrix - Commander 2021, led by Adrix and Nev, Twincasters
Swell the Host - Commander 2015, led by Ezuri, Claw of Progress
Temur Roar - Tarkir: Dragonstorm Commander, led by Eshki, Temur's Roar

Commanders that run Rapid Hybridization most

Deck counts from EDHREC.

Hakbal of the Surging Soul: 17,057 decks
Ureni of the Unwritten: 12,457 decks
Zinnia, Valley's Voice: 8,590 decks
Vivi Ornitier: 8,076 decks
Zimone, Infinite Analyst: 6,462 decks
Eluge, the Shoreless Sea: 5,800 decks
Alela, Cunning Conqueror: 5,404 decks
Urza, Lord High Artificer: 5,129 decks

Often played with Rapid Hybridization

Cards that show up in the same decks on EDHREC.

Rulings

2013-01-24: If the creature is an illegal target when Rapid Hybridization tries to resolve, it won't resolve and none of its effects will happen. No Frog Lizard token will be created.
2013-07-01: If Rapid Hybridization resolves and the creature isn't destroyed (perhaps because it has indestructible), its controller will still get the Frog Lizard token.