
Each player who controls a multicolored creature draws a card. Then destroy all creatures.
Depopulate has 5 printings, first in Streets of New Capenna (2022). EDHREC ranks it #10,731 among Commander cards. It appears most in Zurgo Helmsmasher decks (1,435 on EDHREC).
Deck counts from EDHREC.
Cards that show up in the same decks on EDHREC.